Placebo Quotes

Skeptics might argue that pharmaceutical companies will fight anything that casts their products in a dubious light - especially if it results in people using lower doses across the board - but the truth is that, for many drug companies, reliable information on the placebo effect can't come soon enough. To pass muster, a drug must outperform placebo. But a 2001 study of antidepressant drug trials showed that while drug efficacy is rising, placebo rates are rising faster. It's almost ironic; the factors behind this are many and varied, but a significant contributor is our society's knowledge of - and belief in - the power of medicines. The pharmaceutical industry's palpable success means that unless something radical happens, it could soon be, like the Red Queen, running to stand still. ~ Michael Brooks

There is a major problem with reliance on placebos, like most vitamins and antioxidants. Everyone gets upset about Big Science, Big Pharma, but they love Big Placebo. ~ Michael Specter

In all technai or arts (medicine perhaps most of all), there is a self-exhilaration on the part of the practitioner (the intoxication of the ego with its own potency) which is infectious: the patient enjoys a placebo-effect which redounds to the ego of the "artist." ~ Kenny Smith

Stein resented the sedative power of religion, or rather the repose available to those blissfully ignorant that the medicament was a fictitious blank. In this exile from peace of mind to which his reason doomed him, he was like an insomniac driven to awaken sleepers from dreams illegitimately won by going around shouting, 'Don't you realize it was a placebo!' Thus it seemed to me that what you were up against in Stein was not logic rampant, but frustrated faith. He could not forgive God for not existing. ~ Peter De Vries

Placebo effect is where the drug causes greater effect and thereby faith accentuates, prolongs and promulgates the strength of the drug. Faith in an object that is known creates a strength in the object's reaction in a more powerful manner, provided the object was intended to create positive in the first place. Yet if this faith is turned inward in a negative manner, it can hinder the effectiveness of the drug or creative power of the thing being used for the positive, this is called the nocebo effect. ~ L.B. Ó Ceallaigh

Music has touched me deeply, sometimes to tears. But at the same time it's been life-affirming, because I've been grateful for the fact that I'm alive and human and capable of being so moved. ~ Brian Molko

My psychiatrist diagnosed me a Hypochondriac. I said, "Okay, can you prescribe me a placebo?"

"Not for Type-2 Hypochondriacs," he said. Your types would just fake faking. Then we'd have a real problem. ~ Brian Spellman

Occult Medicine is essentially sympathetic. Reciprocal affection, or at least real goodwill, must exist between doctor and patient. Syrups and juleps have very little inherent virtue; they are what they become through the mutual opinion of operator and subject; hence homoeopathic medicine dispenses with them and no serious inconvenience follows. ~ Eliphas Levi

In vaccine trials the placebo for the control group is often an aluminum-containing vaccine. That fact alone could account for why so many mainstream-approved research studies have inconclusive and perhaps even contradictory outcomes. ~ James Morcan

Prayer may be a placebo for the disease of helplessness, but placebos can make you feel better. ~ David Mitchell

Because a heart that hurts, is a heart that works. ~ Placebo

Dr Stewart Wolf took the placebo effect to the limit. He took two women who were suffering with nausea and vomiting, one of them pregnant, and told them he had a treatment which would improve their symptoms. In fact he passed a tube down into their stomachs (so that they wouldn't taste the revolting bitterness) and administered ipecac, a drug that which should actually induce nausea and vomiting. Not only did the patients' symptoms improve, but their gastric contractions - which ipecac should worsen - were reduced. His results suggest - albeit it in a very small sample - that a drug could be made to have the opposite effect to what you would predict from the pharmacology, simply by manipulating people's expectations. In this case, the placebo effect outgunned even the pharmacological influences. More ~ Ben Goldacre

The seemingly impossible can become possible! You Are the Placebo, the new book by Dr. Joe Dispenza ~ Joe Dispenza

When people think about a placebo such as the royal touch, they usually dismiss it as "just psychology." But, there is nothing "just" about the power of a placebo, and in reality it represents the amazing way our mind controls our body. ~ Dan Ariely

One clear-cut fact does, however, emerge: placebos, prescribed for a paranoid schizophrenic by his authority referent, had served to inhibit for approximately two or three months, not imaginary pains, but somatic ones. This finding is probably the most striking of all the findings reported herein for either Joseph or Leon. It demonstrates most dramatically the positive effects which can be achieved by suggestions originating with the paranoid schizophrenic's own delusional authority figures. This finding is all the more remarkable when one remembers that paranoid schizophrenics are typically negativistic, that, because they view other people with suspicion and mistrust, they resist suggestions that others make. But our data clearly suggest that paranoid schizophrenics are, like everyone else, quite capable of following positive suggestions when they originate with positive referents. In this respect, the major difference between normal people and paranoid schizophrenics lies not so much in the fact that the schizophrenics are less suggestible but in the fact that they have no positive authorities or referents in the real world; if they have any at all, these positive referents exist only in the world of their delusions. ~ Milton Rokeach

The big bulk of the response to antidepressants is the placebo response. ~ Irving Kirsch

What early Christianity meant by 'faith' (pistis) was initially nothing other than running ahead and clinging to a model or idea whose attainability was still uncertain. Faith is purely anticipatory, in the sense that it already has an effect when it mobilizes the existence of the anticipatory towards the goal through anticipation. In analogy for the placebo effect, one would have to call this the movebo effect. ~ Peter Sloterdijk

Either it is true that a medicine works or it isn't. It cannot be false in the ordinary sense but true in some alternative sense. If a therapy or treatment is anything more than a placebo, properly conducted double-blind trials, statistically analyzed, will eventually bring it through with flying colours. Many candidates for recognition as orthodox medicines fail the test and are summarily dropped. The alternative label should not (though, alas, it does) provide immunity from the same fate. ~ Richard Dawkins

Stef is officially the sexiest member of Placebo ~ Brian Molko

I felt Mr Willard had deserted me. I thought he must have planned it all along, but Buddy said No, his father simply couldn't stand the sight of sickness and especially his own son's sickness, because he thought all sickness was sickness of the will. Mr Willard had never been sick a day in his life. ~ Sylvia Plath

I was a traditional teacher for a time, but my students would ride the energy. I wanted to free people not give them a placebo. ~ Frederick Lenz

When conventional medicine fails, when we must confront pain and death, of course we are open to other prospects for hope.
And, after all, some illnesses are psychogenic. Many can be at least ameliorated by a positive cast of mind. Placebos are dummy drugs, often sugar pills. Drug companies routinely compare the effectiveness of their drugs against placebos given to patients with the same disease who had no way to tell the difference between the drug and the placebo. Placebos can be astonishingly effective, especially for colds, anxiety, depression, pain, and symptoms that are plausibly generated by the mind. Conceivably, endorphins -the small brain proteins with morphine-like effects - can be elicited by belief. A placebo works only if the patient believes it's an effective medicine. Within strict limits, hope, it seems, can be transformed into biochemistry. ~ Carl Sagan

We often give painkillers the credit that ought to be given to the passage of time, the belief that they would kill the pain, or the water that accompanied them. ~ Mokokoma Mokhonoana

Sham ultrasound is beneficial for dental pain, placebo operations have been shown to be beneficial in knee pain (the surgeon just makes fake keyhole surgery holes in the side and mucks about for a bit as if he's doing something useful), and placebo operations have even been shown to improve angina. That's ~ Ben Goldacre

You have to believe in a placebo or it won't work, but if it works, it's obviously working in some indirect way, through feedback in the immune system, let us say, or in the willpower of the patient to take a more strenuous exercise in their own therapy. ~ Charles Jencks

Give someone who has faith in you a placebo and call it a hair growing pill, anti-nausea pill or whatever, and you will be amazed at how many respond to your therapy. ~ Bernie Siegel

Testing intermittent use (3 times a week), a recent study showed a similar result with zolpidem (Ambien). After several weeks of use, those taking this sleeping pill were sleeping better when they took the drug but then worse when they skipped it.[26] Overall, after several weeks of use, their sleep was averaging no better than a group taking inactive placebo. ~ Daniel F. Kripke

It's known that stress gives rise to disease. It's also known that many diseases, especially stress-related diseases, can be cured by placebos - pills that have no medicinal effect, but people think they do, and so they do. ~ Richard Dawkins

But this anti-war protest, is far from a success; it is just a placebo for the people. These peacemakers feel so satisfied, gratified; gay-gallant-and-gleeful. But they do not achieve anything acceptable, perceptible; or peaceful. ~ Joss Sheldon

To be less dumb, remember your propensity for post hoc postulation and the power positive permutations of the placebo effect have to pollute your perspicacity. ~ David McRaney

I do a lot of research on the placebo effect, not just in depression but in irritable bowel syndrome, pain, arthritis of the knee, migraine, asthma. ~ Irving Kirsch

Only massage therapists seemed to be informed about trigger points and referred pain, and only exceptional individuals among them (in my own experience at least) were treating trigger points effectively. What's more, the burgeoning variety of unproven modalities offered by massage therpaists gave the profession such an aura of flakiness that the elegant science of myofascial pain got unfairly confused with treatments whose results could easily be attributed to the placebo effect. ~ Clair Davies

They also observed that the amygdala in the vaccinated monkeys didn't mature with time as it was supposed to. The amygdala, incidentally, plays an important role in social interactions. Maybe it's not so surprising they also observed that in the vaccinated monkeys the opioid antagonist diprenorphine (DPN) levels never lowered throughout the study. In the placebo group, the DPN levels decreased noticeably. One function of DPN is to block social interaction. What this means is the research showed that the social behavior of those monkeys that received the actual vaccines, where the DPN levels did not decrease, turned anti-social. We found there was at least one more study undertaken to verify the association between DPN and social behavior. Performed in 1981[141]. The authors of that study believe the release of opioids in the brain encourages social interactions. So, when the body fails to decrease the amount of the antagonist DPN, it not only blocks the opioids that encourage social interactions, but it blocks the desire to socially interact. ~ James Morcan

For people who are depressed, and especially for those who do not receive enough benefit from medication of for whom the side effects of antidepressants are troubling, the fact that placebos can duplicate much of the effects of antidepressants should be taken as good news. It means that there are other ways of alleviating depression. As we have seen, treatments like psychotherapy and physical exercise are at least as effective as antidepressant drugs and more effective than placebos. In particular, CBT has been shown to lower the risk of relapsing into depression for years after treatment has ended, making it particularly cost effective. ~ Irving Kirsch

Two large trials of antioxidants were set up after Peto's paper (which rather gives the lie to nutritionists' claims that vitamins are never studied because they cannot be patented: in fact there have been a great many such trials, although the food supplement industry, estimated by one report to be worth over $50 billion globally, rarely deigns to fund them). One was in Finland, where 30,000 participants at high risk of lung cancer were recruited, and randomised to receive either ß-carotene, vitamin E, or both, or neither. Not only were there more lung cancers among the people receiving the supposedly protective ß-carotene supplements, compared with placebo, but this vitamin group also had more deaths overall, from both lung cancer and heart disease. The results of the other trial were almost worse. It was called the 'Carotene and Retinol Efficacy Trial', or 'CARET', in honour of the high p-carotene content of carrots. It's interesting to note, while we're here, that carrots were the source of one of the great disinformation coups of World War II, when the Germans couldn't understand how our pilots could see their planes coming from huge distances, even in the dark. To stop them trying to work out if we'd invented anything clever like radar (which we had), the British instead started an elaborate and entirely made-up nutritionist rumour. Carotenes in carrots, they explained, are transported to the eye and converted to retinal, which is the molecule that detects light in the ~ Ben Goldacre

I never thought I'd say this, but I miss voter fraud. ~ Jon Stewart

Like antidepressants, a substantial part of the benefit of psychotherapy depends on a placebo effect, or as Moerman calls it, the meaning response. At least part of the improvement that is produced by these treatments is due to the relationship between the therapist and the client and to the client's expectancy of getting better. That is a problem for antidepressant treatment. It is a problem because drugs are supposed to work because of their chemistry, not because of the psychological factors. But it is not a problem for psychotherapy. Psychotherapists are trained to provide a warm and caring environment in which therapeutic change can take place. Their intention is to replace the hopelessness of depression with a sense of hope and faith in the future. These tasks are part of the essence of psychotherapy. The fact that psychotherapy can mobilize the meaning response - and that it can do so without deception - is one of its strengths, no one of its weaknesses. Because hopelessness is a fundamental characteristic of depression, instilling hope is a specific treatment for it it. Invoking the meaning response is essential for the effective treatment of depression, and the best treatments are those that can do this most effectively and that can do without deception. ~ Irving Kirsch

Placebo is music for outsiders, by outsiders and our gigs are like conventions of outcasts, which is cool. ~ Brian Molko

I often felt better as soon as I swallowed my vitamin C, long before it had time to take effect. Medical researchers call it 'placebo effect'; I prefer to call it magic, for it occurs when something - a pill or a word - is imbued with power and meaning, and so it becomes effective. That is alchemy. ~ Kat Duff

Can we teach them that they are the placebo? In other words, can we convince them that instead of investing their belief in the known, like a sugar pill or a saline injection, they can place their belief in the unknown and make the unknown known? And really that's what this book is about: empowering you to realize that you have all the biological and neurological machinery to do exactly that. My goal is to demystify these concepts with the new science of the way things really are so that it is within the reach of more people to change their internal states in order to create positive changes in their health and in their external world. If that sounds too amazing to be true, then as I've said, toward the end of the book you'll see some of the research compiled from our workshops to show you exactly how it's possible. What ~ Joe Dispenza

The placebo effect is one of the most fascinating things in the whole of medicine. It's not just about taking a pill, and your performance and your pain getting better. It's about our beliefs and expectations. It's about the cultural meaning of a treatment. ~ Ben Goldacre

Consider the clinicaltrials by which drugs are tested in human subjects.5 Before a new drug can enter the market, its manufacturer must sponsor clinicaltrials to show the Food and Drug Administration that the drug is safe and effective, usually as compared with a placebo or dummy pill. The results of all the trials (there may be many) are submitted to the FDA, and if one or two trials are positive - that is, they show effectiveness without serious risk - the drug is usually approved, even if all the other trials are negative. ~ Marcia Angell

Doctor, I'd like a bottle of placebo please. ~ Candess M. Campbell

When it comes to dead bodies in current psychotropic trials, there are a greater number of them in the active treatment groups than in the placebo groups. This is quite different from what happens in penicillin trials or trials of drugs that really work. -David Healy (282) ~ Robert Whitaker

Religion is now viewed by many as a placebo or emotional crutch precisely because that is how we often pitch the gospel to unbelievers ~ J.P. Moreland

Like ugly Asian babies, valid superstitions don't exist. At best, any perceived effect of a superstition is you merely psyching yourself out. Think of it as an asshole placebo. ~ Orlando Winters

There is an almost linear relationship between the methodological quality of a homeopathy trial and the result it gives. The worse the study - which is to say, the less it is a "fair test" - the more likely it is to find that homeopathy is better than placebo. ~ Ben Goldacre

Worship is a meeting at the center so that our lives are centered in God and not lived eccentrically. We worship so that we live in response to and from this center, the living God. Failure to worship consigns us to a life of spasms and jerks, at the mercy of every advertisement, every seduction, every siren. Without worship we live manipulated and manipulating lives. We move in either frightened panic or deluded lethargy as we are, in turn, alarmed by specters and soothed by placebos. If there is no center, there is no circumference. ~ Edmund Clowney

He points out that mystics have always worked systematically to modify their brain chemistry, whether through fasting, self-flagellation, sleeplessness, hypnotic movement, or chanting.* The brain can be made to drug itself, as seems to happen with certain placebos. We don't merely imagine that the placebo antidepressant is working to lift our sadness or worry - the brain is actually producing extra serotonin in response to the mental prompt of swallowing a pill containing nothing but sugar and belief. What all this suggests is that the workings of consciousness are both more and less materialistic than we usually think: chemical reactions can induce thoughts, but thoughts can also induce chemical reactions. ~ Michael Pollan

A man doesn't need a study to know if he's feeling amorous. There is no such thing as a placebo erection. ~ Chris Kilham

Placebos can be astonishingly effective, especially for colds, anxiety, depression, pain, and symptoms that are plausibly generated by the mind. Conceivably, endorphins - the small brain proteins with morphinelike effects - can be elicited by belief. A placebo works only if the patient believes it's an effective medicine. Within strict limits, hope, it seems, can be transformed into biochemistry. As ~ Carl Sagan