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The gradual depletion of the ozone layer and the related "greenhouse effect" has now reached crisis proportions as a consequence of industrial growth, massive urban concentrations and vastly increased energy needs. Industrial waste, the burning of fossil fuels, unrestricted deforestation, the use of certain types of herbicides, coolants and propellants: all of these are known to harm the atmosphere and environment. ~ Pope John Paul II
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The Panic of 1819 exerted a profound effect on American economic thought. As the first great financial depression, similar to a modern expansion-depression pattern, the panic heightened interest in economic problems, and particularly those problems related to the causes and cures of depressed conditions. ~ Murray Rothbard
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Skeptics might argue that pharmaceutical companies will fight anything that casts their products in a dubious light - especially if it results in people using lower doses across the board - but the truth is that, for many drug companies, reliable information on the placebo effect can't come soon enough. To pass muster, a drug must outperform placebo. But a 2001 study of antidepressant drug trials showed that while drug efficacy is rising, placebo rates are rising faster. It's almost ironic; the factors behind this are many and varied, but a significant contributor is our society's knowledge of - and belief in - the power of medicines. The pharmaceutical industry's palpable success means that unless something radical happens, it could soon be, like the Red Queen, running to stand still. ~ Michael Brooks
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But even more than her diary, Shimamura was surprised at her statement that she had carefully cataloged every novel and short story she had read since she was fifteen or sixteen. The record already filled ten notebooks.
"You write down your criticisms, do you?"
"I could never do anything like that. I just write down the author and the characters and how they are related to each other. That is about all."
"But what good does it do?"
"None at all."
"A waste of effort."
"A complete waste of effort," she answered brightly, as though the admission meant little to her. She gazed solemnly at Shimamura, however.
A complete waste of effort. For some reason Shimamura wanted to stress the point. But, drawn to her at that moment, he felt a quiet like the voice of the rain flow over him. He knew well enough that for her it was in fact no waste of effort, but somehow the final determination that it had the effect of distilling and purifying the woman's existence. ~ Yasunari Kawabata
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Dr Stewart Wolf took the placebo effect to the limit. He took two women who were suffering with nausea and vomiting, one of them pregnant, and told them he had a treatment which would improve their symptoms. In fact he passed a tube down into their stomachs (so that they wouldn't taste the revolting bitterness) and administered ipecac, a drug that which should actually induce nausea and vomiting. Not only did the patients' symptoms improve, but their gastric contractions - which ipecac should worsen - were reduced. His results suggest - albeit it in a very small sample - that a drug could be made to have the opposite effect to what you would predict from the pharmacology, simply by manipulating people's expectations. In this case, the placebo effect outgunned even the pharmacological influences. More ~ Ben Goldacre
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Mademoiselle De Lafontaine – in right of her father, who was a German, assumed to be psychological, metaphysical and something of a mystic – now declared that when the moon shone with a light so intense it was well known that it indicated a special spiritual activity. The effect of the full moon in such a state of brilliancy was manifold. It acted on dreams, it acted on lunacy, it acted on nervous people; it had marvelous physical influences connected with life. Mademoiselle related that here cousin, who was mate of a merchant ship, having taken a nap on deck on such a night, lying on his back, with his face full in the light of the moon, had wakened, after a dream of an old woman clawing him by the cheek, with his features horribly drawn to one side; and his countenance had never quite recovered its equilibrium. ~ J. Sheridan Le Fanu
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The fact that the crime and the punishment were related and bound up in the form of atrocity was not the result of some obscurely accepted law of retaliation. It was the effect, in the rites of punishment, of a certain mechanism of power: of a power that not only did not hesitate to exert itself directly on bodies, but was exalted and strengthened by its visible manifestations; of a power that asserted itself as an armed power whose functions of maintaining order were not entirely unconnected with the functions of war; of a power that presented rules and obligations as personal bonds, a breach of which constituted an offence and called for vengeance; of a power for which disobedience was an act of hostility, the first sign of rebellion, which is not in principle different from civil war; of a power that had to demonstrate not why it enforced its laws, but who were its enemies, and what unleashing of force threatened them; of a power which, in the absence of continual supervision, sought a renewal of its effect in the spectacle of its individual manifestations; of a power that was recharged in the ritual display of its reality as 'super-power'. ~ Michel Foucault
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Type II trauma also often occurs within a closed context - such as a family, a religious group, a workplace, a chain of command, or a battle group - usually perpetrated by someone related or known to the victim. As such, it often involves fundamental betrayal of the relationship between the victim and the perpetrator and within the community (Freyd, 1994). It may also involve the betrayal of a particular role and the responsibility associated with the relationship (i.e., parent-child, family member-child, therapist-client, teacher-student, clergy-child/adult congregant, supervisor-employee, military officer-enlisted man or woman). Relational dynamics of this sort have the effect of further complicating the victim's survival adaptations, especially when a superficially caring, loving or seductive relationship is cultivated with the victim (e.g., by an adult mentor such as a priest, coach, or teacher; by an adult who offers a child special favors for compliance; by a superior who acts as a protector or who can offer special favors and career advancement). In a process labelled "selection and grooming", potential abusers seek out as potential victims those who appear insecure, are needy and without resources, and are isolated from others or are obviously neglected by caregivers or those who are in crisis or distress for which they are seeking assistance. This status is then used against the victim to seduce, coerce, and exploit. Such a scenario can lead to trauma bonding between ~ Christine A. Courtois
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To be less dumb, remember your propensity for post hoc postulation and the power positive permutations of the placebo effect have to pollute your perspicacity. ~ David McRaney
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The remoter poetry in particular was replete with effects, an effect being something hypnotic we cannot quite understand, whiteness of moon and wave related to the setting of Time in a manner "too subtle for the intellect." And all over Europe, by the late 19th century, poets had decided that effects were intrinsic to poetry, and were aiming at them by deliberate process. By the end of the century, in France, whole poems have been made "too subtle for the intellect," held together, as effects are, by the extra-semantic affinities of their words. Picking up a name that was once thrown around as their authors, we have learned to call them "Symbolist" poems. In the Symbolist poem the Romantic effect has become a structural principle, and we may say that Symbolism is scientific Romanticism, thus an effort to anticipate the work of time by aiming directly at the kind of existence a poem may have when a thousand years have deprived it of its dandelions and its mythologies, an existence purely linguistic, determined by the molecular bonds of half-understood words. ~ Hugh Kenner
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We often give painkillers the credit that ought to be given to the passage of time, the belief that they would kill the pain, or the water that accompanied them. ~ Mokokoma Mokhonoana
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Placebo effect is where the drug causes greater effect and thereby faith accentuates, prolongs and promulgates the strength of the drug. Faith in an object that is known creates a strength in the object's reaction in a more powerful manner, provided the object was intended to create positive in the first place. Yet if this faith is turned inward in a negative manner, it can hinder the effectiveness of the drug or creative power of the thing being used for the positive, this is called the nocebo effect. ~ L.B. Ó Ceallaigh
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I think there is a general misconception that you write poems because you "have something to say." I think, actually, that you write poems because you have something echoing around in the bone-dome of your skull that you cannot say. Poetry allows us to hold many related tangential notions in very close orbit around each other at the same time. The "unsayable" thing at the center of the poem becomes visible to the poet and reader in the same way that dark matter becomes visible to the astrophysicist. You can't see it, but by measure of its effect on the visible, it can become so precise a silhouette you can almost know it. ~ Rebecca Lindenberg
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The placebo effect is one of the most fascinating things in the whole of medicine. It's not just about taking a pill, and your performance and your pain getting better. It's about our beliefs and expectations. It's about the cultural meaning of a treatment. ~ Ben Goldacre
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Only massage therapists seemed to be informed about trigger points and referred pain, and only exceptional individuals among them (in my own experience at least) were treating trigger points effectively. What's more, the burgeoning variety of unproven modalities offered by massage therpaists gave the profession such an aura of flakiness that the elegant science of myofascial pain got unfairly confused with treatments whose results could easily be attributed to the placebo effect. ~ Clair Davies
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The language and the "people" of the unconscious are symbols, and the means of communications dreams.
Thus an examination of Man and his Symbols is in effect an examination of man's relation to his own unconscious. And since in Jung's view the unconscious is the great guide, friend, and adviser of the conscious, this book is related in the most direct terms to the study of human beings and their spiritual problems. ~ C. G. Jung
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An important attribute of metabolites is their close relationship to both the biological states of interest (i.e. disease status) and relevant genomic, transcriptomic, and proteomic variants causally related to the disease state. As such, metabo-profiles can be viewed as an intermediate measure that links pre-disposing genes and environmental exposures to a resulting disease state. Causal metabolites also typically have a stronger relationship (i.e. larger effect size) to the underlying genetics and the disease phenotype. Thus, the integration of metabolomic data into systems biology approaches may provide a missing link between genes and disease states. ~ Joseph Loscalzo
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In all technai or arts (medicine perhaps most of all), there is a self-exhilaration on the part of the practitioner (the intoxication of the ego with its own potency) which is infectious: the patient enjoys a placebo-effect which redounds to the ego of the "artist." ~ Kenny Smith
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People who are contented and serene sleep well. They fall asleep easily, stay asleep, and wake refreshed. Conversely, people who are anxious, stressed, or depressed do not sleep well, and chronic insomnia is strongly associated with mood disorders. These are clear correlations, but what is cause and what is effect is not clear. Most experts agree that sleep and mood are closely related, that healthy sleep can enhance emotional well-being, while insufficient quantity or quality of sleep can adversely affect it. ~ Andrew Weil
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The loudness of tone in Jane Eyre is undoubtedly effective in communicating tension and frustration, but the style does of course have its related limitations. It precludes the use of the small suggestive detail or the quiet but telling observation that Mrs Gaskell and George Eliot are so good at. In such a fortissimo performance
as this, the pianissimo gets drowned out, or noted only as an incongruity (which helps to account for the book's moments of unintended comic bathos). Again, it makes the whole question of modulation of tone a difficult one,6 and it is also hard to manage irony elegantly, as the Brocklehurst and Ingram portraits show.
There is unconscious ambiguity but little deliberate irony in Jane Eyre. Hence the remarkable unity of critical interpretation of the book - the reader knows all too well what he is meant to think about the heroine and the subsidiary characters. The novel does not merely request our judicious sympathy for the heroine, it demands
that we see with her eyes, think in her terms, and hate her enemies, not just intermittently (as in David Copperfield) but in toto. It was, incidentally, because James Joyce recognised the similar tendency of Stephen Hero that he reshaped his autobiographical material as A Portrait of the Artist as a Young Man, retaining the 'first-person effect' but building in stylistic and structural
irony that would guard against the appearance of wholesale authorial endorsement of Stephen. ~ Ian Gregor
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I never thought I'd say this, but I miss voter fraud. ~ Jon Stewart
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I often felt better as soon as I swallowed my vitamin C, long before it had time to take effect. Medical researchers call it 'placebo effect'; I prefer to call it magic, for it occurs when something - a pill or a word - is imbued with power and meaning, and so it becomes effective. That is alchemy. ~ Kat Duff
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It dawned on me at some point that our music makes certain people happy - I never thought we'd have that effect and it's really gratifying and humbling. My least favorite is the exhaustion that comes with traveling a lot, the touring related exhaustion. And the crazy thing is that we've all been doing this for years and your body never gets used to it - you always feel messed up. But it's a good problem to have. ~ David Macklovitch
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I am not a climatologist, but I don't think any of the other witnesses are either. I do work in the related field of atomic, molecular and optical physics. I have spent my professional life studying the interactions of visible and infrared radiation with gases - one of the main physical phenomena behind the greenhouse effect. I have published over 200 papers in peer reviewed scientific journals. ~ William Happer
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Reincarnation is not an exclusively Hindu or Buddhist concept, but it is part of the history of human origin. It is proof of the mindstream's capacity to retain knowledge of physical and mental activities. It is related to the theory of interdependent origination and to the law of cause and effect. ~ Dalai Lama
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A good deal of the corporate planning I have observed is like a ritual rain dance; it has no effect on the weather that follows, but those who engage in it think it does. Moreover, it seems to me that much of the advice and instruction related to corporate planning is directed at improving the dancing, not the weather. ~ Russell L. Ackoff
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Like ugly Asian babies, valid superstitions don't exist. At best, any perceived effect of a superstition is you merely psyching yourself out. Think of it as an asshole placebo. ~ Orlando Winters
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I do a lot of research on the placebo effect, not just in depression but in irritable bowel syndrome, pain, arthritis of the knee, migraine, asthma. ~ Irving Kirsch
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It is related of a Swedish priest that, profoundly disturbed by the sight of the effect his address produced upon the auditors, who were dissolved in tears, he said soothingly, "Children, do not weep; the whole thing might be a lie. ~ Soren Kierkegaard
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What early Christianity meant by 'faith' (pistis) was initially nothing other than running ahead and clinging to a model or idea whose attainability was still uncertain. Faith is purely anticipatory, in the sense that it already has an effect when it mobilizes the existence of the anticipatory towards the goal through anticipation. In analogy for the placebo effect, one would have to call this the movebo effect. ~ Peter Sloterdijk
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Like antidepressants, a substantial part of the benefit of psychotherapy depends on a placebo effect, or as Moerman calls it, the meaning response. At least part of the improvement that is produced by these treatments is due to the relationship between the therapist and the client and to the client's expectancy of getting better. That is a problem for antidepressant treatment. It is a problem because drugs are supposed to work because of their chemistry, not because of the psychological factors. But it is not a problem for psychotherapy. Psychotherapists are trained to provide a warm and caring environment in which therapeutic change can take place. Their intention is to replace the hopelessness of depression with a sense of hope and faith in the future. These tasks are part of the essence of psychotherapy. The fact that psychotherapy can mobilize the meaning response - and that it can do so without deception - is one of its strengths, no one of its weaknesses. Because hopelessness is a fundamental characteristic of depression, instilling hope is a specific treatment for it it. Invoking the meaning response is essential for the effective treatment of depression, and the best treatments are those that can do this most effectively and that can do without deception. ~ Irving Kirsch
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A plain narrative of any remarkable fact, emphatically related, has a more striking effect without the author's comment. ~ William Shenstone
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People with the halo effect seem to know exactly what they're doing and, moreover, make you want to admire them for it. ~ Walter Isaacson
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Because Nature always balances her books, the Sun lost some velocity in the transaction; but the effect would not be measurable for a few thousand years. ~ Arthur C. Clarke
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No civilisation, not even that of ancient Greece, has ever undergone such a continuous and profound process of change as Western Europe has done during the last 900 years. It is impossible to explain this fact in purely economic terms by a materialistic interpretation of history. The principle of change has been a spiritual one and the progress of Western civilisation is intimately related to the dynamic ethos of Western Christianity, which has gradually made Western man conscious of his moral responsibility and his duty to change the world. ~ Christopher Dawson
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Faith is not simply a private matter, or something we practice once a week at church. Rather, it should have a contagious effect on the broader world. Jesus used these images to illustrate His kingdom.: a sprinkle of yeast causing the whole loaf to rise, a pinch of salt preserving a slab of meat, the smallest seed in the garden growing into a great tree in which birds of the air come to nest. ~ Philip Yancey
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Who is to say that prayers have any effect? On the other hand, who is to say they don't? I picture the gods, diddling around on Olympus, wallowing in the nectar and ambrosia and the aroma of burning bones and fat, mischievous as a pack of ten-year-olds with a sick cat to play with and a lot of time on their hands. 'Which prayer shall we answer today?' they ask one another. 'Let's cast the dice! Hope for this one, despair for that one, and while we're at it, let's destroy the life of that woman over there by having sex with her in the form of a crayfish!' I think they pull a lot of their pranks because they're bored. ~ Margaret Atwood
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the core of the existing principle of the rule of law: that all persons and authorities within the state, whether public or private, should be bound by and entitled to the benefit of laws publicly made, taking effect (generally) in the future and publicly administered in the courts. ~ Tom Bingham
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Once the primary bonds which gave security to the individual are severed, once the individual faces the world outside of himself as a completely separate entity, two courses re-open to him since he has to overcome the unbearable state of powerlessness and aloneness. By one course he can progress to "positive freedom"; he can relate himself spontaneously to the world in love and work, in the genuine expression of his emotional, sensuous and intellectual capacities; he can thus become one again with man, nature, and himself, without giving up the independence and integrity of his individual self. The other course open to him is to fall back, to give up his freedom, and to try to overcome his aloneness by eliminating the gap that has arisen between his individual self and the world. This second course never reunites him with the world in the way he was related to it before he merged as an "individual," for the fact of his separateness cannot be reversed; it is an escape from an unbearable situation which would make life impossible if it were prolonged. This course of escape, therefore, is characterized by its compulsive character, like every escape from threatening panic; it is also characterized by the more or less complete surrender of individuality and the integrity of the self. Thus it is not a solution which leads to happiness and positive freedom; it is, in principle, a solution which is to be found in all neurotic phenomena. It assuages an unbearable anxiety and makes lif ~ Erich Fromm
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Singing other people's material was perceived, I think, as a weakness of my persona. The effect, though, was to make me dig my heels in and try even harder to combine the two. ~ Rickie Lee Jones
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When I say something untrue on the air, I mean for it to be transparently untrue. I assume people know when I'm just saying something for effect. Or to be funny. ~ Ira Glass
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It [realization of Oneness] means being constantly open to the possibility that we are like two flowers looking at each other from two different branches of the same tree, so that if we were to go deep enough inside to the trunk, we would realize that we are one. Just being open to this possibility will have a profound effect on your relationships and on your experience of the world. ~ Francis Lucille
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Staying on the treadmill is one thing, and I do think it's related to staying true to our commitments even when we're not comfortable. But getting back on the treadmill the next day, eager to try again, is in my view even more reflective of grit. Because when you don't come back the next day - when you permanently turn your back on a commitment - your effort plummets to zero. As a consequence, your skills stop improving, and at the same time, you stop producing anything with whatever skills you have. ~ Angela Duckworth
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Secondly, the nature of the revolutions which have altered the surface of the earth must have had a more decisive effect on the terrestrial quadrupeds than on the marine animals. ~ Georges Cuvier
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Violent action is unclear to most of those who get caught up in it. Experience is fragmentary; cause and effect,why and how, are torn apart. Only sequence exists. First this then that. And afterward, for those who survived, a lifetime of trying to understand ~ Salman Rushdie
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To "those about to marry," Ibsen therefore says in effect, "Be sure you are not in love!" And to those who are in love he says, "Part! ~ Henrik Ibsen
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