Blood Brain Barrier Quotes

lots of fruit and vegetables gives us all the vitamins we need. A lot is said about anti-oxidants these days. I do agree with the beneficial effects they might have on our health, and the possible need to have a good intake of them on a daily basis. As I have said, I eat a very healthy diet, with lots of fresh vegetables and fruit. I have never taken any anti-oxidant supplements, other than garlic pills, but am considering doing so. There is no proof that these anti-oxidants get through the blood-brain barrier, so they may not actually help us. I feel that a controlled double-blind study should be done on this subject. There ~ John Pepper

One way aluminum (Al) can penetrate the blood brain barrier is by hiding in Trojan horse-like fashion inside a macrophage (Mφ). ~ James Morcan

A healthy body means a healthy mind. You get your heart rate up, and you get the blood flowing through your body to your brain. Look at Albert Einstein. He rode a bicycle. He was also an early student of Jazzercise. You never saw Einstein lift his shirt, but he had a six-pack under there. ~ Steve Carell

A large piece of lead floated out of Bobby head, followed by dark chunks of what could only be pieces of Bobby's brain.

The torrent started up again. It flowed steady rather than pulsed with his heart. I knew from that, and from the amount of blood, that it was that mofo vein bleeding. And probably more than a small tear if the amount of blood was telling. I thought there had to be a hole the size of Montana in that thing.

"Jesus Mother Mary" I said, then "Stitch!"

The scrub tech slapped a needle holder into my palm, a curved needle and silk stitch clamped into the end of it. I might have closed my eyes - I've been told I do that sometimes in surgery when I'm trying to visualize something - though if so I don't remember doing it. I took that needle and aimed it into the pool of blood.

"Suck here Joe, right here."

When I thought I could see something, something gray and not black red, I plunged the pointy end of the needle through whatever the visible tissue was and looped it out again. I cinched it down and tied it quick, then repeated the maneuver again after adjusting slightly for lighting, sweating, my own bounding heartbeat, and the regret I wasn't wearing my own diaper.
We're losing, I thought. ~ Edison McDaniels

Blood is no longer flowing in my brain right now. It's somewhere else. ~ Kenya Wright

Wave after wave, Ralph followed the rise and fall until something of the remoteness of the sea numbed his brain. Then gradually the almost infinite size of this water forced itself oh his attention. This was the divider, the barrier. On the other side of the island, swathed at midday with mirage, defended by the shield of the quiet lagoon, one might dream of rescue; but here, faced by the brute obtuseness of the ocean, the miles of division, one was clamped down, one was helpless, one was condemned, one was- ~ William Golding

There's a psychologist called Mary & Diamond who at Brooklyn in California, in the 80s studied rats. And they took rats at different ages. Newborns, some of whom they deliberately brain damaged, adult, middle-aged, elderly rats. And they exposed these rats to different levels of environmental stimulation, better food, more playmates, toys to play with and so on.

They found out a couple of months later that the rats, at any age, including the brain-damaged rats, who had the better stimulation, they were smarter. But in the autopsy then they also found that in the front part of their brain they had larger nerve-cells with more connections with other nerve-cells and richer blood supply. In other words that environmental stimulation actually caused a change in the state of the brain, even in the older rats.

And that's called neuroplasticity. The capacity of the brain to develop new circuits. So whether it comes to ADHD, addiction, depression or other childhood disorders or any other issue with adults as well, if we recognize them not as ingrained, genetically-determined diseases, but as problems of development, then the question becomes very different. Then the question becomes not just "how do we treat the symptoms?" (and addiction itself is a symptom, depression is a symptom), but "how do we help people develop out of these conditions?"

In other words, it is not a medical question, purely, but a developmental question. And development always ~ Gabor Mate

It was a dagger in the haughty father's heart, an arrow in his brain, to see how the flesh and blood he could not disown clung to this obscure stranger, and he sitting by. Not that he cared to whom his daughter turned, or from whom turned away. The swift sharp agony struck through him, as he thought of what his son might do. ~ Charles Dickens

I am interested in the way that we look at a given landscape and take possession of it in our blood and brain. None of us lives apart from the land entirely; such an isolation is unimaginable. ~ N. Scott Momaday

It is as though horror has frozen the blood in my veins, paralyzed my arms, and torn all thought from my brain with the swipe of a paw. I sit there, flying on, and continue to stare, as though mesmerised, at the Cauldron on my left. ~ Ernst Udet

Metabolically active cells, such as those of the liver, kidneys, muscles, and brain, have hundreds or thousands of mitochondria, making up some 40 per cent of the cytoplasm. The egg cell, or oocyte, is exceptional: it passes on around 100000 mitochondria to the next generation. In contrast, blood cells and skin cells have very few, or none at all; sperm usually have fewer than 100. All in all, there are said to be 10 million billion mitochondria in an adult human, which together constitute about 10 per cent of our body weight. ~ Nick Lane

How marvelous it all is! Built not by saints and angels, but the work of men's hands; cemented with men's honest blood and with a world of tears, welded by the best brains of centuries past; not without the taint and reproach incidental to all human work, but constructed on the whole with pure and splendid purpose. Human, and yet not wholly human
for the most heedless and the most cynical must see the finger of the Divine. ~ Archibald Primrose, 5th Earl Of Rosebery

I wrapped his pistol in his cap, and with the butt of the gun - not the end of the butt, but the side - hit him hard on the head. You read a lot about people being hit on the head and knocked out, but you don't read much about blood clots in the brain. In actual fact, though, it's a delicate matter, hitting a man on the head, ~ Jack Finney

THE ACCIDENT maybe you read it in the paper i was so young just a child i did something stupid nightstand by the bed found it in the drawer that was so often locked but not this time sunlight through curtains high noon reflected on polished steel heavy in my hand pretending to be a cop like my father but more like dirty harry like i saw on tv my little brother burst into the room four years old just four years old without thinking i aimed killer instinct squeeze tug bang slow motion exploding blood not a sound from him as if what happened was completely natural i replay it again and again efficient little hum that burning memory pulled the trigger and watched him fold like a house of cards and the questions hammer through my brain and i ask you again "how much more do i have to pay before becoming whole again? ~ Thee Karkajou Automaton

Heart; I named my lass sweetly;
She danced to the mundane tunes of daftness;
By nature she was midsummer madness;
Or rather a reckless, careless, devil-may-care colleen.

I pampered all her hefty desires;
Brain; my friend said treat her with caution;
For she is a child; doesn't ruminate her action;
You are mother, with deep devotion.

And one fine day came the tempest darling;
She named him love, besotted and infatuated;
Enchanted by his charms, smelled the roses;
Failed to see the thorns that pricked.

And drip-drip-drip, the blood it dripped;
When her beloved tossed and crushed her core;
She knew not how to stand up straight;
I opened my eyes and the driblets fell.

Don't nurse her; said my friend; my brain;
For she is a demented lass not worth the pain;
She will go away when her wounds are dried;
To her unmoved brutal hero, Love.

A mother cannot be unmoved, I cried;
For all this time, I held her high;
I knocked at your door, you flinty villain;
Not to hear, all that you said.

Call me a demon or a dragon;
For all I will say is don't nurse the brat;
Let her bleed and cry for some more time;
She will get up; for she is your child.

All he said was unerred truth;
She bled and nursed her own wounds;
She drove me to her hero's place; And said,

"This is where my poem stays. ~ Ranjani Ramachandran

Finally, someone had seen him.
And what had he done? Let her get away. Undermined by his disgusting human anatomy. It had just been made excruciatingly clear to him that the human male brain and the human male c*ck couldn't both sustain sufficient amounts of blood to function at the same time. It was one or the other, and the human male apparently didn't get to choose which one. As a Tuatha Dé, he would have been in complete control of his lust. Desirous yet coolheaded, perhaps even a touch bored (it wasn't as if he could do something he hadn't done before; given a few thousand years, a Tuatha Dé got around to trying everything).
But as a human male, lust was far more intense, and his body was apparently slave to it. A simple hard-on could turn him into a bloody Neanderthal. ~ Karen Marie Moning

The miracle left him dumbfounded, that his heart had not yet shirked its weary task of pumping his bored blood through his brain. ~ Janny Wurts

The point is, the brain talks to itself, and by talking to itself changes its perceptions. To make a new version of the not-entirely-false model, imagine the first interpreter as a foreign correspondent, reporting from the world. The world in this case means everything out- or inside our bodies, including serotonin levels in the brain. The second interpreter is a news analyst, who writes op-ed pieces. They read each other's work. One needs data, the other needs an overview; they influence each other. They get dialogues going.

INTERPRETER ONE: Pain in the left foot, back of heel.
INTERPRETER TWO: I believe that's because the shoe is too tight.
INTERPRETER ONE: Checked that. Took off the shoe. Foot still hurts.
INTERPRETER TWO: Did you look at it?
INTERPRETER ONE: Looking. It's red.
INTERPRETER TWO: No blood?
INTERPRETER ONE: Nope.
INTERPRETER TWO: Forget about it.
INTERPRETER ONE: Okay.

Mental illness seems to be a communication problem between interpreters one and two.

An exemplary piece of confusion.

INTERPRETER ONE: There's a tiger in the corner.
INTERPRETER TWO: No, that's not a tiger- that's a bureau.
INTERPRETER ONE: It's a tiger, it's a tiger!
INTERPRETER TWO: Don't be ridiculous. Let's go look at it.

Then all the dendrites and neurons and serotonin levels and interpreters collect themselves and trot over to the corner.
If you are not crazy, the second inte ~ Susanna Kaysen

The only shame George Webber felt was that at one time in his life, for however short a period, he broke bread and sat at the same table with any man when the living warmth of friendship was not there; or that he ever traded upon the toil of his brain and the blood of his heart to get the body of a scented whore that might have been better got in a brothel for some greasy coins. This was the only shame he felt. And this shame was so great in him that he wondered if all his life thereafter would be long enough to wash out of his brain and blood the last pollution of its loathsome taint. ~ Thomas Wolfe

To judge from the entrance the dawn was making, it promised to be a very iffy day
that is, blasts of angry sunlight one minute, fits of freezing rain the next, all of it seasoned with sudden gusts of wind
one of those days when someone who is sensitive to abrupt shifts in weather and suffers them in his blood and brain is likely to change opinion and direction continuously, like those sheets of tin, cut in the shape of banners and roosters, that spin every which way on rooftops with each new puff of wind. ~ Andrea Camilleri

When you're in love, your brain secretes endorphins into your blood. Organic morphine leaks out of a gland in your skull, feels like a low-grade opium rush. Some people confuse the two, the head rush and the love. You think you're in love with a person, but you're in love with a syringe. ~ Craig Clevenger

Fee, fi, fo, fum, I smell the blood of a Christian man, Be he dead, be he living, with my brand, I'll dash his brains from his brain-pan. ~ Joseph Jacobs

Ebola Zaire attacks every organ and tissue in the human body except skeletal muscle and bone. It is a perfect parasite because it transforms virtually every part of the body into a digested slime of virus particles. The seven mysterious proteins that, assembled together, make up the Ebola-virus particle, work as a relentless machine, a molecular shark, and they consume the body as the virus makes copies of itself. Small blood clots begin to appear in the bloodstream, and the blood thickens and slows, and the clots begin to stick to the walls of blood vessels. This is known as pavementing, because the clots fit together in a mosaic. The mosaic thickens and throws more clots, and the clots drift through the bloodstream into the small capillaries, where they get stuck. This shuts off the blood supply to various parts of the body, causing dead spots to appear in the brain, liver, kidneys, lungs, intestines, testicles, breast tissue (of men as well as women), and all through the skin. ~ Richard Preston

In the end he became as fragmentary as the poems of Sappho he never succeeded in restoring, and finally one morning he looked up into the face of the woman who'd been the greatest love of his life and failed to recognize her. And then there was another kind of blow inside his head; blood pooled in his brain for the last time, washing even the last fragments of his self away. ~ Jeffrey Eugenides

Meditation is one of Mother Nature's most powerful medicines and has no apparent side effects. It's been scientifically proven that meditation helps calm the mind and de-stress the body. It also helps regulate blood pressure, lowers depression, induces the 'relaxation response', rewires the circuitry of your brain, enhances positive emotions, increases overall life satisfaction . . . And that's just for starters! ~ Melissa Ambrosini

If we reason we would be understood; if we imagine we would that the airy children of our brain were born anew within another's; if we feel we would that another's nerves should vibrate to our own, that the beams of their eyes should kindle at once and mix and melt into our own; that lips of motionless ice should not reply to lips quivering and burning with the heart's best blood. This is love. ~ Percy Bysshe Shelley

Ghosts can haunt damned near anything. I have heard them in the breathy voice of a song and seen them between the covers of a book. They have hidden in trees so that their faces peer out of the bark, and hovered beneath the silver surface of water. They disguise themselves as cracks in concrete or come calling in a delirium of fever. On summer days they keep pace like the shadow of our shadow. They lurk in the breath of young girls who give us our first kiss. I've seen men who were haunted to the point of madness by things that never were and things that should have been. I've seen ghosts in the lines on a woman's face and heard them in the jangling of keys. The ghosts in fire freeze and the ghosts in ice burn. Some died long ago; some were never born. Some ride the blood in my veins until it reaches my brain. Sometimes I even mistake myself for one. Sometimes I am one. ~ Damien Echols

Individuals who rate high on the so-called Anxiety Sensitivity Index, or ASI, have a high degree of what's known as interoceptive awareness, meaning they are highly attuned to the inner workings on their bodies, to the beepings and bleatings, the blips and burps, of their physiologies; they are more conscious of their heart rate, blood pressure, digestive burblings, and so forth than other people are. ~ Scott Stossel

She'd been so docile that Nina had become concerned. "Maybe she's not getting enough blood to her
brain?" she'd murmured to Matthias. ~ Leigh Bardugo

When trying to exclude brain hemorrhage, remember that blood is hyperattenuated (bright) and usually measures 35-45 Housfield units (HU). This has the opposite appearance to infarction, which is typically hypoattenuated (dark) when compared to normal brain parenchyma. ~ Rocky Saenz

Thyroid Panel (blood test)-Abnormal thyroid hormone levels are a common cause of anxiety, depression, forgetfulness, confusion, and lethargy. Having low thyroid levels decreases overall brain activity, which can impair your thinking, judgment, and self-control and make it very hard for you to feel good. Low thyroid functioning can make it nearly impossible to manage weight effectively. To know your thyroid levels, you need to know these figures: thyroid-stimulating hormone (TSH) Free T3 Free T4 Thyroid antibodies (thyroid peroxidase and thyroglobulin antibodies) ~ Daniel Amen

Moreno, Morelos, Cantine, Gomez, Gutierrez, Villanousul, Ureta, Licon, Navarro, Iturbi; Jorge, Filomena, Nena, Manuel, Jose, Tomas, Ramona. This man walked and this man sang and this man had three wives; and this man died of this, and that of that, and the third from another thing, and the fourth was shot, and the fifth was stabbed and the sixth fell straight down dead; and the seventh drank deep and died dead, and the eighth died in love, and the ninth fell from him horse, and the tenth coughed blood, and the eleventh stopped his heart, and the twelfth used to laugh much, and the thirteenth was a dancing one, and the fourteenth was most beautiful of all, the fifteenth had ten children and the sixteenth is one of those children as is the seventeenth; and the eighteenth was Tomas and did well with his guitar; the next three cut maize in their fields, had three lovers each; the twenty-second was never loved; the twenty-third sold tortillas, patting and shaping them each at the curb before the Opera House with her little charcoal stove; and the twenty-fourth beat his wife and now she walks proudly in the town and is merry with new men and here he stands bewildered by this unfair thing, and the twenty-fifth drank several quarts of river with his lungs and was pulled forth in a net, and the twenty-sixth was a great thinker and his brain now sleeps like a burnt plum in his skull. ~ Ray Bradbury

With air, you can struggle for a time. If you've trained in a Fish-Suit, you can struggle quite some time. However, without blood to your brain a few seconds is all it takes to become unconscious. Keep it up a few seconds more and that brief sleep can be extended by hours. A few more seconds and you can kill someone. It was all in the timing. Too little and they'd wake up whilst you were about your business. Too much and you'd kill them. ~ G.R. Matthews