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The best diet for overall health, and specifically for heart, brain, and cancer risk reduction, is a diet that's aggressively low in carbohydrates with an abundance of healthful fat, and this is the central theme of 'Grain Brain.'
David Perlmutter Quotes: The best diet for overall
Gluten is this Generation's Tobacco
David Perlmutter Quotes: Gluten is this Generation's Tobacco
The Mediterranean diet is rich in fruits and vegetables while low in sodium. It is also enriched with olive oil, high in antioxidants as well as monounsaturated and polyunsaturated fats.
David Perlmutter Quotes: The Mediterranean diet is rich
It may seem draconian, but the best recommendation I can make is to completely avoid grains.
David Perlmutter Quotes: It may seem draconian, but
Archives of Internal Medicine revealed that postmenopausal women who were put on statin drugs to lower their cholesterol had a nearly 48 percent increased risk of developing diabetes compared to those who weren't given the drug.
David Perlmutter Quotes: Archives of Internal Medicine revealed
Dementia is our most-feared illness, more than heart disease or cancer.
David Perlmutter Quotes: Dementia is our most-feared illness,
New science reveals that exercise positively influences the gut's balance of bacteria to favor colonies that prevent weight gain.
David Perlmutter Quotes: New science reveals that exercise
One recent study performed by the American Medical Association and published in the _Archives of Internal Medicine_ in January 2012 demonstrated an astounding 48 percent increased risk of diabetes among women taking statin medications.

This study involved big numbers -- more than one hundred sixty thousand postmenopausal women -- making it hard to ignore its significance and gravity. Recognizing that type 2 diabetes is a powerful risk factor for Alzheimer's disease, a relationship between statin drugs and cognitive decline or cognitive dysfunction is certainly understandable.
~ David Perlmutter, M.D., _Grain Brain_
David Perlmutter Quotes: One recent study performed by
Mental fitness is served by consciously redirecting our attention away from the constant bombardment from the media whose reason to be seems to be focused on keeping us in a state of constant alert.
David Perlmutter Quotes: Mental fitness is served by
Parkinson's is described as a progressive idiopathic neurodegenerative disorder, a brain disease that will worsen with time for which no cause has as yet been identified.
David Perlmutter Quotes: Parkinson's is described as a
The origin of brain disease is in many cases predominantly dietary. Although several factors play into the genesis and progression of brain disorders, to a large extent numerous neurological afflictions often reflect the mistake of consuming too many carbs and too few healthy fats.
David Perlmutter Quotes: The origin of brain disease
The bottom line is that this author, a practicing neurologist dealing with Alzheimer's disease on a daily basis, believes we need to expand the public awareness that modifiable lifestyle factors have a profound role to play in determining who will or won't get this disease.
David Perlmutter Quotes: The bottom line is that
Food is medicine. We can actually change our gene expressions with the foods we eat.
David Perlmutter Quotes: Food is medicine. We can
This low-fat idea that's been drummed into our heads and bellies is completely off-base and deeply responsible for most of our modern ills.
David Perlmutter Quotes: This low-fat idea that's been
Antioxidants are chemicals that break down or neutralize the damaging effects of free radicals - chemicals produced as a byproduct of normal cellular metabolism.
David Perlmutter Quotes: Antioxidants are chemicals that break
The science supporting the relationship between carbohydrates and dementia is quite exciting, as it paves the way for lifestyle changes that can profoundly affect a person's chances of remaining intact, at least from a brain perspective.
David Perlmutter Quotes: The science supporting the relationship
It's now generally accepted that Mesmer was actually treating psychosomatic illness, and he profited mightily from people's gullibility. In retrospect, his theories and practices sound ridiculous, but in truth, the story of Mesmer parallels many stories of today. It's not so ridiculous to imagine people falling prey to products, procedures, and health claims that are brilliantly marketed. Every day we hear of some news item related to health. We are bombarded by messages about our health - good, bad, and confusingly contradictory. And we are literally mesmerized by these messages. Even the smart, educated, cautious, and skeptical consumer is mesmerized. It's hard to separate truth from fiction, and to know the difference between what's healthful and harmful when the information and endorsements come from "experts.
David Perlmutter Quotes: It's now generally accepted that
When we are exposed to a real or perceived threatening situation, powerful things happen in the brain to memorialize aspects of the event, including all manner of associated circumstances like where, when and how it occurred.
David Perlmutter Quotes: When we are exposed to
Rarely, Type 2 diabetes develops without any readily identifiable predisposing factor. But in the great majority of cases, it is brought on by lifestyle activities, including, and clearly most importantly, dietary choices.
David Perlmutter Quotes: Rarely, Type 2 diabetes develops
Alzheimer's is a disease for which there is no effective treatment whatsoever. To be clear, there is no pharmaceutical agent, no magic pill that a doctor can prescribe that will have any significant effect on the progressive downhill course of this disease.
David Perlmutter Quotes: Alzheimer's is a disease for
Indeed, Dr. Cahill and other researchers have determined that beta-HBA, which is easily obtainable just by adding coconut oil to your diet, improves antioxidant function, increases the number of mitochondria, and stimulates the growth of new brain cells. In chapter 5 we
David Perlmutter Quotes: Indeed, Dr. Cahill and other
he gave the first modern-day description of the condition in children in a lecture at a London hospital in 1887, noting, "If the patient can be cured at all, it must be by means of diet.
David Perlmutter Quotes: he gave the first modern-day
Eat your vegetables. Brush your teeth. Sweat once in a while. Get plenty of rest. Don't smoke. Laugh more. There are certain tenets to health that are pretty commonsensical and that we all know we should practice routinely.
David Perlmutter Quotes: Eat your vegetables. Brush your
When a child is watching television, he or she is not involved in play, not socializing with other individuals, and most importantly, not receiving feedback as to the actions or consequences of his or her behavior.
David Perlmutter Quotes: When a child is watching
We are designed to be smart people our entire lives. The brain is supposed to work well until our last breath.
David Perlmutter Quotes: We are designed to be
Children need to be exploring their physical world. They need to be learning the fundamental laws of physics by manipulating objects.
David Perlmutter Quotes: Children need to be exploring
Carbs are devastating for the brain.
David Perlmutter Quotes: Carbs are devastating for the
The idea that people are nutritionally deprived because they don't eat grain has no scientific basis.
David Perlmutter Quotes: The idea that people are
Our best medical journals are now brimming with high-profile, rigorous studies that show a stunning correlation between high blood sugar and risk for dementia.
David Perlmutter Quotes: Our best medical journals are
As reported in the New England Journal of Medicine in 2013, even slight elevations of blood sugar that are far below the diabetes range have been shown to significantly increase the risk for the development of untreatable dementia.7
David Perlmutter Quotes: As reported in the New
People are getting to this place of understanding that their lifestyle choices actually do matter a whole lot as opposed to this notion that you live your life, come what may, and hope for a pill.
David Perlmutter Quotes: People are getting to this
Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicated on inflammation.
David Perlmutter Quotes: Inflammation is the cornerstone of
Humans are not the fastest or the strongest animals on the planet, but when it comes to survival, we have had the unique advantage of being clever.
David Perlmutter Quotes: Humans are not the fastest
Most grain foods, whether we're talking about quinoa, amaranth, the very popular grains of the day - the reality is they still are associated with a carbohydrate surge.
David Perlmutter Quotes: Most grain foods, whether we're
While the hippocampus itself doesn't store memories, it serves to triage our experiences based upon their survival significance.
David Perlmutter Quotes: While the hippocampus itself doesn't
We can change the expression of more than 70 percent of the genes that have a direct bearing on our health and longevity.
David Perlmutter Quotes: We can change the expression
So-called 'complex carbs' may actually represent a more significant threat to health than simple sugar in that they may not only raise blood sugar, but keep it elevated for a more prolonged period of time.
David Perlmutter Quotes: So-called 'complex carbs' may actually
Although microbial testing kits are starting to emerge on the market,
David Perlmutter Quotes: Although microbial testing kits are
As a practicing neurologist, I can tell you first hand that working with Parkinson's patients offers clinical challenges. But from an emotional perspective, this disease can border on overwhelming.
David Perlmutter Quotes: As a practicing neurologist, I
In general, the public knowledge base and thus decision-making behaviors are far more influenced by advertisement than with current science.
David Perlmutter Quotes: In general, the public knowledge
As a practicing neurologist, I place central importance in applying current science to the notion of disease prevention.
David Perlmutter Quotes: As a practicing neurologist, I
Our ancestors relied upon their advanced brains to survive during times of food shortage, and fortunately, the human brain is able to utilize body fat as an extremely efficient fuel to sustain function when glucose-providing food is unavailable.
David Perlmutter Quotes: Our ancestors relied upon their
Researchers have known for some time now that the cornerstone of all degenerative conditions, including brain disorders, is inflammation. But what they didn't have documented until now are the instigators of that inflammation - the first missteps that prompt this deadly reaction. And what they are finding is that gluten, and a high-carbohydrate diet for that matter, are among the most prominent stimulators of inflammatory pathways that reach the brain.
David Perlmutter Quotes: Researchers have known for some
statins may lessen brain function and increase risk for heart disease. The reason is simple: The brain needs cholesterol
David Perlmutter Quotes: statins may lessen brain function
Elevated blood sugar stirs up inflammation in the bloodstream, as excess sugar can be toxic if it's not swept up and used by cells. It also triggers a reaction called glycation - the biological process by which sugar binds to proteins and certain fats, resulting in deformed molecules that don't function well. These sugar proteins are technically called advanced glycation end products (AGEs). The body does not recognize AGEs as normal, so they set off inflammatory reactions. In the brain, sugar molecules and brain proteins combine to produce lethal new structures that contribute to the degeneration of the brain and its functioning. The relationship between poor blood sugar control and Alzheimer's disease in particular is so strong that researchers are now calling Alzheimer's disease type-3 diabetes.14
David Perlmutter Quotes: Elevated blood sugar stirs up
Strokes are categorized as either bleeding into the brain or a blockage in blood supply, known as an ischemic stroke. The latter are overwhelmingly more common, compromising about 87 percent of all stroke events.
David Perlmutter Quotes: Strokes are categorized as either
A fundamental premise in cancer therapy is trying to identify how the metabolism of cancer cells differs from normal tissue. When differences are identified, it often paves the way for treatments that will disrupt the cancer's metabolism while sparing normal tissue.
David Perlmutter Quotes: A fundamental premise in cancer
The biggest issue by far is that carbohydrates are absolutely at the cornerstone of all of our major degenerative conditions.
David Perlmutter Quotes: The biggest issue by far
The neurons in the gut are so innumerable that scientist are now calling the totality of them "the second brain"...

In fact, recent research is revaling that our second brain may not be second at all. It can act independently from the main brain and control many functions without the brain's input.
David Perlmutter Quotes: The neurons in the gut
Memory enhancement self-help programs abound and promise improved memory performance by the utilization of any number of seemingly unique techniques focused on the context of how information is encoded.
David Perlmutter Quotes: Memory enhancement self-help programs abound
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